2026Journal articleFree to read
Zorlu Ö, Karabağ S, Özkan M, Beyhan Yılmaz M, Yıkmış S
Frontiers in medicine
Background Repeated ultraviolet (UV) exposure promotes oxidative stress, extracellular matrix remodeling, and disruption of dermoepidermal architecture, all of which contribute to skin photoaging. Although green tea derivatives have been investigated for photoprotective effects, the impact of oral whole-leaf matcha powder on cumulative UV-induced skin changes remains insufficiently characterized. The aim of this study was to investigate whether oral whole-leaf matcha powder was associated with attenuation of UV-induced dermoepidermal disruption, collagen phenotype alterations, and skin surface changes in a rat model of repeated UV exposure. Methods Thirty-two female Sprague–Dawley rats were randomly assigned to Control, UV, Matcha, and UV + Matcha groups ( n = 8/group). Matcha was administered orally at 50 mg/kg/day for 30 days. Experimental photoaging was induced using a repeated UV exposure protocol comprising 15 sessions over 4 weeks. Histomorphometric evaluation of dermoepidermal architecture, collagen phenotype, and elastic fiber parameters was performed together with serum antioxidant enzyme measurements and macroscopic skin surface analyses. Results Compared with controls, repeated UV exposure increased epidermal thickness ( p = 0.001), reduced the interdigitation index ( p = 0.002), decreased type I collagen and the type I/III collagen ratio ( p < 0.001 and p = 0.001, respectively), increased type III collagen ( p = 0.016), and reduced glutathione reductase activity ( p < 0.001). UV exposure was also associated with higher surface texture indices, including FFT roughness and local variance (both p < 0.001), as well as an increased fine wrinkle percentage ( p < 0.001). Compared with the UV group, the UV + Matcha group showed attenuated epidermal thickening ( p =…
Abstract shortened. Read the full abstract at the source.
Abstract text comes from PubMed, OpenAlex or Europe PMC and belongs to the authors and publisher.
Study type
Animal study
Experiments in mice, rats, fish or other animals.
Assigned automatically from the title, abstract and subject terms.
Topics
Matcha is a main subject here (named in the title).
Zorlu Ö, Karabağ S, Özkan M, Beyhan Yılmaz M, Yıkmış S. (2026). Oral whole-leaf matcha partially attenuates UV-induced dermoepidermal disruption and collagen phenotype alterations in a rat model of repeated photoaging. Frontiers in medicine. https://doi.org/10.3389/fmed.2026.1813454
DOI: 10.3389/fmed.2026.1813454 · PubMed ID: 42359064
Japanese matcha is a type of powdered green tea, grown in a traditional way. Shading of the plants during the growth period enhances the processes of synthesis and accumulation of biologically active compounds, including theanine,…
ReviewCognition, mood and stressAntioxidants and polyphenolsL-theanine and caffeineCited 321×Theanine, a major amino acid in green tea, exhibits a stress-reducing effect in mice and humans. Matcha, which is essentially theanine-rich powdered green tea, is abundant in caffeine. Caffeine has a strong antagonistic effect against…
Randomized controlled trialCognition, mood and stressAntioxidants and polyphenolsL-theanine and caffeineCited 84×Background: Green tea is traditionally known to induce mental clarity, cognitive function, physical activation and relaxation. Recently, a special green tea, matcha tea, is rapidly gaining popularity throughout the world and is frequently…
ReviewCognition, mood and stressAntioxidants and polyphenolsL-theanine and caffeineCited 70×Matcha tea is gaining popularity throughout the world in recent years and is frequently referred to as a mood-and-brain food. Previous research has demonstrated that three constituents present in matcha tea, l-theanine, epigallocatechin…
Randomized controlled trialCognition, mood and stressAntioxidants and polyphenolsL-theanine and caffeineCited 66×